My Big Brain on Human Hormones

My Big Brain on Human HormonesOn 6 August 1991 the World Wide Web was opened up to the public. On that day in history I was a computer science techie programming in Silicon Valley. Yup, it’s okay to call me a geek and Yes, I do like math.

I continued working in Silicon Valley through the mid-90’s until I retired to be a sensual researcher. I mention this now because that nerdy inquisitive, data-gathering, puzzle-solving intellectual side of me has been quite useful in my menopause research. I am questioning my assumptions and the popular ideas regarding menopause, so at times I take that big brain out for a spin. On this ride I explore menopause and hormones.

Hormones…I ponder what I’d heard and thought I knew. Everyone knows that it’s your hormones that cause menopause, especially all the troubles right? Lowering estrogen and progesterone I’d heard of. I'm pretty sure those hormones are made in the ovaries and that they are the hormones that are replaced when a woman undergoes hormone replacement therapy (HRT). But as I think on it, I'm not entirely sure about even this little bit of information. I had more doubts the further I went into the topic, so I backed up a bit.

Do I even know what a hormone is? What exactly is a hormone's role within the body? How many hormones does the human body have? When did science discover and begin working with hormones? How much does science understand about hormones?

As I informed myself a picture developed based on facts I found of interest. Starting with the most basic information I got clear on what a hormone is and what they do. Hormones are chemicals present in all multi-cellular organisms. Hormones are the body's cellular communication system. When you get more than one cell together to make a living thing, those cells need to coordinate with each other. Nature came up with hormones to be the messengers between individual cells, tissues and organs. Hormones regulate metabolism, all of the chemical and energy reactions in the body. Inside the human body hormones help maintain a constant state of critical things such as temperature, amount of water and salts, and amount of sugar. Hormones tell the body when it needs rest, when to wake from sleep and when to go into a high state of alert.  Hormones regulate growth, sexual reproduction and more.

In 1902 the first definitive proof was discovered that a hormone exists. The first hormone identified was secretin. The rest of the century marked huge growth for the field of endocrinology including two new hunger hormones discovered in the 1990’s. Currently science has identified over 100 naturally occurring human hormones that tell our cells or organs to do something or to stop doing something. Names I'd heard, but didn't realize were human hormones began popping to mind. Insulin is a hormone. Adrenaline is a hormone. Steroids are an entire class of hormones which includes the commonly known sex hormones. Estrogen is a subclass of steroid hormones containing three distinct hormones. The list of human hormones goes on...serotonin, testosterone, dopamine, oxytocin.

Some of the most recent research on hormones and human behavior shows that hormones don’t cause things, they modulate them. The messages or information that a hormone delivers is contained in the interactions between hormones not only in the individual hormone itself. It also shows that the brain monitors not just hormone levels, but the rate at which hormone levels are changing. Nobody is entirely sure how our bodies do it, but to me all of this points to a wonderfully complex, robust and adaptive system that science does not entirely understand.

One of the many things I did as a tech geek is build personal computers from components like motherboards, RAM, hard drives, etc. then install the operating system and application software and test the completed computers. They were called IBM clones in those days. I would build each in the same way, typically 10 at a time, using the same components and following the same recipe for installing the software. Then I’d put together the entire computer network and train people how to use them. You would expect that each machine would perform the same. The name clone implies it. However, more often than not, each machine, even as identical as I could make them, would have individual idiosyncrasies. I’d have to make adjustments to get around some of those quirks. I didn’t think it should be that way, they were clones after all. But it was that way and to do my job effectively I stopped expecting it to be any different. I explained it away, that it must be due to tiny differences in electrical components and materials, but I never really knew why.

Now I’m thinking, here we have the human body with far more complex interconnected natural systems tweaked and tuned by nature for many thousands of years. It would be foolish of me to think that a woman’s hormonal system in major transition could be so easily explained. While doing research, again I was surprised at how fuzzy my knowledge was on the topic of hormones. Yet I have so readily agreed with the stereotype and stigma society tosses out about menopausal women, you know - it’s her hormones, as if I know the full implication of what it means.

Where does that leave me? My nerd side wants to go on a quest for more details to fill in the blanks, but from my sensualist perspective I am most interested in my experience of life. My head was clearing up on the topic. I could separate fact from mystery. I could wrap my mind around the fact that there are things about our bodies that we experience moment to moment, yet science is at a loss to explain why or how.

Becoming aware of my propensity to want to qualify and quantify my experience and look to science for answers, I also realized that there could be an entirely different way of going through the change and approaching midlife. I appreciate science and facts, but it is not my goal to become a medical or scientific expert. Do I even have a goal related to menopause? Getting informed had freed me up. It is also clear that I would be looking elsewhere for what would guide me through this transition. 

3 comments:

Richard said...

That's interesting about your experience with computer clones that you built having individual propensities, and how much even more complex women's bodies are. I would think that your quest to clear up society's myths about menopause would have wider and more positive effects on women then going the other direction, breaking it down to molecular scale, which can be fascinating but in the end, benefits drug companies more than anyone.

Yvonne Wray said...

Thank you for your thoughts Richard. I am happy to see you as a man here, finding out about menopause. I firmly believe knowing a woman's experiences has benefits for all of us.

Katima said...

Like what you have to say about this. . . I sometimes feel my hormones are messed up by continued exposure to electro magnetic currents from being on the computer for my work. There is a parallel between computers and out bodies in many ways. Thanks for writing this! (Sharing)

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